Cheng-Yu Tsai Selected Research

APTO-253

1/2018	APTO-253 Is a New Addition to the Repertoire of Drugs that Can Exploit DNA BRCA1/2 Deficiency.
1/2018	APTO-253 Stabilizes G-quadruplex DNA, Inhibits MYC Expression, and Induces DNA Damage in Acute Myeloid Leukemia Cells.

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Cheng-Yu Tsai Research Topics

Disease

10	Neoplasms (Cancer) 05/2021 - 12/2010
3	Pleural Effusion (Pleural Effusions) 01/2022 - 01/2019
3	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 05/2021
2	Pancreatic Neoplasms (Pancreatic Cancer) 12/2022 - 09/2020
2	Osteoporosis 05/2022 - 01/2021
2	Compression Fractures (Compression Fracture) 05/2022 - 01/2021
2	Inflammation (Inflammations) 02/2022 - 01/2018
2	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2016
2	Pneumonia (Pneumonitis) 08/2019 - 01/2019
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2018 - 01/2018
2	Astrocytoma (Pilocytic Astrocytoma) 08/2014 - 12/2013
1	Hemolysis 10/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2022
1	Obstructive Sleep Apnea 04/2022
1	LEOPARD Syndrome (Syndrome, LEOPARD) 01/2022
1	Ovarian Neoplasms (Ovarian Cancer) 01/2022
1	Pleurisy (Pleuritis) 01/2022
1	Spinal Diseases (Disease, Spinal) 01/2022
1	Pulmonary Tuberculosis 01/2022
1	Apnea 10/2021
1	Lung Neoplasms (Lung Cancer) 01/2021
1	Dementia (Dementias) 01/2021
1	Cognitive Dysfunction 01/2021
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021
1	Pancreatic Diseases (Pancreatic Disease) 09/2020
1	Pancreatitis 09/2020
1	Chronic Obstructive Pulmonary Disease (COPD) 08/2019
1	Hypersensitivity (Allergy) 01/2018
1	Asthma (Bronchial Asthma) 01/2018
1	Leukemia 01/2018
1	Lymphoma (Lymphomas) 01/2018
1	Acute Promyelocytic Leukemia 01/2018
1	Carcinogenesis 01/2018
1	Congenital Abnormalities (Deformity) 01/2016
1	Neurocytoma 01/2014
1	Oligodendroglioma 01/2014

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 09/2020 - 12/2013
3	Biomarkers (Surrogate Marker)IBA 04/2022 - 01/2019
3	Particulate MatterIBA 01/2022 - 08/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 06/2009
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2022 - 05/2021
2	CateninsIBA 05/2021 - 05/2021
2	Pharmaceutical PreparationsIBA 09/2020 - 01/2018
2	EnzymesIBA 09/2020 - 07/2010
2	APTO-253IBA 01/2018 - 01/2018
1	Lidocaine (Xylocaine)FDA LinkGeneric 12/2022
1	Antimicrobial PeptidesIBA 10/2022
1	CarbonIBA 02/2022
1	AnionsIBA 02/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2022
1	CationsIBA 02/2022
1	IonsIBA 02/2022
1	InterleukinsIBA 02/2022
1	Carboplatin (JM8)FDA LinkGeneric 01/2022
1	Vorinostat FDA Link 01/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	Bortezomib (Velcade)FDA Link 01/2022
1	ATP dependent 26S protease (26S proteasome)IBA 01/2022
1	Temozolomide (Temodar)FDA LinkGeneric 05/2021
1	Heavy MetalsIBA 01/2021
1	Nerve Growth Factor (NGF)IBA 01/2021
1	Cholinergic Agents (Cholinergics)IBA 01/2021
1	BuffersIBA 09/2020
1	Aspartate-Ammonia Ligase (Asparagine Synthetase)IBA 09/2020
1	Asparaginase (Elspar)FDA Link 09/2020
1	antiarrhythmic peptide (AAP)IBA 09/2020
1	MetalsIBA 01/2019
1	olaparibIBA 01/2018
1	Interleukin-33IBA 01/2018
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2018
1	NIMA-Interacting Peptidylprolyl IsomeraseIBA 01/2018
1	Phosphotransferases (Kinase)IBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2018
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2018
1	Trypan Blue FDA Link 01/2018
1	Oncogene Proteins (Oncogene Protein)IBA 01/2018
1	CytokinesIBA 01/2018
1	Interleukin Receptors (Interleukin Receptor)IBA 01/2018
1	cis-trans-IsomerasesIBA 01/2018
1	tau Proteins (tau Protein)IBA 01/2016
1	Cisplatin (Platino)FDA LinkGeneric 08/2014
1	Copper Transporter 1IBA 08/2014
1	Aurora Kinase AIBA 08/2014
1	TubulinIBA 08/2014
1	Death-Associated Protein KinasesIBA 01/2014
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2014
1	CalciumIBA 01/2014
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2014
1	WW Domain-Containing OxidoreductaseIBA 12/2013
1	Metalloproteases (Metalloproteinases)IBA 01/2012
1	Matrix Metalloproteinases (MMPs)IBA 01/2012

Therapy/Procedure

4	Therapeutics 05/2021 - 04/2010
3	Pedicle Screws 01/2022 - 01/2016
1	Pancreatectomy 12/2022
1	Minimally Invasive Surgical Procedures 05/2022
1	Cochlear Implantation 01/2022
1	Chemoradiotherapy 05/2021
1	Immunotherapy 01/2021
1	Drug Therapy (Chemotherapy) 01/2021